JHMI Graduate Student - BCMB Program
BA 2000 - University of Dublin, Trinity College, Ireland. Major in Biochemistry
Research Interests
The function and significance of the majority of recently described post translational modifications occurng on the globular core of the nucleosome remain unknown. Employing yeast genetics we hope to probe for their role at tanscriptionally silent regions of the genome.
Publications
Hyland, E.M., Cosgrove, M.S., Molina, H., Wang, D., Pandey, A., Cotter, R.J., and Boeke, J.D. Insights into the role of Histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae. 2005 MCB 25: 10060-10070
Hyland, E.M., Rezende, L.F., and Richardson, C.C. The DNA binding domain of the gene 2.5 single stranded DNA binding protein of bacteriophage T7. 2002 J. Biol. Chem 278: 7247-7256.
Mc Gee M.M., Hyland E., Campiani G., Ramunno A., Nacci
V., and Zisterer D.M. Caspase-3 is not essential
for DNA fragmentation in MCF-7 cells during apoptosis
induced by the pyrrolo-1,5-benzoxazepine,
PBOX-6. FEBS Lett. 2002 515(1-3):66-70.
(410) 955-2474
BRB 320
