Robert Yarrington
JHMI Graduate Student - BCMB Program
BSc 2001 Georgia Instutite of Technology, major in Applied Biology
Research Interests
Pmr1:
Manipulating Pmr1, a P-type ATPase in the golgi involved in Ca2+ and Mn2+ transport, to identify novel interactions with, potential drug inhibitors of, and Mn2+ Ty1 RT/RH suppressor mutants.
Ty1 RT/RH:
Investigating the biochemical properties of Ty1 RT/RH mutants identified in screen for suppressors of Mn2+ mediated transposition inhibition..
Publications
JHMI Graduate Student - BCMB Program
BSc 2001 Georgia Instutite of Technology, major in Applied Biology
Research Interests
Pmr1:
Manipulating Pmr1, a P-type ATPase in the golgi involved in Ca2+ and Mn2+ transport, to identify novel interactions with, potential drug inhibitors of, and Mn2+ Ty1 RT/RH suppressor mutants.
Ty1 RT/RH:
Investigating the biochemical properties of Ty1 RT/RH mutants identified in screen for suppressors of Mn2+ mediated transposition inhibition..
Publications
Sulek M, Yarrington R, McGibbon G, Boeke J.D, Junop M. A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homoloous end joining. 2007 DNA Repair 6(12); 1805-1818
Yarrington R.M, Chen J, Bolton E.C, Boeke J.D. Mn2+ suppressor mutations and biochemical communication between Ty1 reverse transcriptase and RNase H domains.2007 J. Virol 81(17); 9004-9012
Richardson S.M, Wheelan S.J, Yarrington R.M, Boeke J.D. GeneDesign; rapid, automated design of multikilobase synthetic genes. 2006 Genome Res 16(4); 550-556
(410) 955-2477
BRB 320
