Biotin labeled oligo nucleotides are used for the development of
diagnostic probes in DNA sequencing. Prices vary depending on the
number of oligos, scale, and type of reagent. Please contact the
Biosynthesis and Sequencing Facility for information on pricing and
availablilty.
Biotin Phosphoramidite is capable of branching to allow multple
biotins at the 3'-or 5'- terminus.
Biotin-dT can replace dT residues within the oligo sequence.
BiotinTEG-CPG is designed for the direct synthesis of oligos
containing biotin on the 3'-terminus.
5' Biotin Phosphramidite is the preferred method of adding a
Biotin to the 5'-terminus. This can only be added once to the
oligonucleotide and can be synthesized with the DMT group on or off,
aiding HPLC or cartridge purification.
BiotinTEG Phosphoramidite contains a 15 atom mixed polarity spacer
arm based on a triethylene glycol. This gives flexibility and optimal
capture by avidin or streptavidin and can be added once or several
times to the 5'- terminus.
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