The Goley Lab is part of the Department of Biological Chemistry at the Johns Hopkins University School of Medicine in Baltimore, MD. We are a bacterial cell biology lab broadly interested in understanding how bacterial cells grow and divide with regularity and accuracy. We use cell biological, biochemical, genetic, and structural approaches to dissect cellular processes with the aim of understanding how they work in molecular detail. A detailed understanding of the fundamental mechanisms of bacterial growth is required to confront the growing crisis in antibacterial resistance. We get really excited about our research.

The Goley Lab recognizes that to do our best and most creative science, we need to include individuals with diverse perspectives, identities, and life experiences. We maintain a safe, inclusive, and equitable lab environment, and we respect and celebrate diversity in all its forms. Erin is committed to individualized and intentional mentoring for all lab members.


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Johns Hopkins University School of Medicine
Latest News
Apr 2020: Wanda’s NSF postdoctoral fellowship was recommended for funding! Congrats Wanda!!!!!
Apr 2020
: Allison gave a talk at the First Virtual Caulobacter Conference! Well done Allison!
Apr 2020
: Erin received the Lee Hood Prize in Biomedical Science from the JHUSOM!
Apr 2020:
Chris’s review and poster on bacterial cell division was published in the Journal of Cell Science. Congrats Chris!
Apr 2020
: The lab was awarded an R35-MIRA from the NIGMS to support our research into the fundamentals of bacterial growth!
Mar 2020
: Jordan’s image made the cover of J Bacteriology! Congrats Jordan!
Jan 2020:
Kousik, Jordan, and Anant’s paper on the role of FtsA in regulating FtsZ superstructure and PG metabolism was accepted to J Bact. Congrats guys!
Jan 2020:
Selam, Allison and Erika’s paper on CdnL function in Caulobacter was accepted to PLoS Genetics! Congrats and thanks to our fantastic collaborators in the Chien, Collier, Cava, and Viollier labs.
Nov 2019:
Erika Smith passed her GBO! Congratulations Erika!
Sep 2019:
BCMB 1st year Jenn Viveiros joined us for her first rotation, and JHU undergrad Shalini Vijayekumar joined us for undergraduate research. Welcome Jenn and Shalini!

Selected Recent Publications
CdnL

The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter (2020) PLOS Genetics
FzlAsummary
An essential regulator of bacterial division links FtsZ to cell wall synthase activation (2019) Curr Biol

FzlAGraphAbs
An FtsZ-binding protein regulates the rate of constriction during Caulobacter cell division.
Lariviere et al (2018) Mol Micro
SLBGraphAbs
FtsZ assembles into species- and disordered linker-dependent superstructures on membranes in vitro.
Sundararajan et al (2018) Mol Micro

Funding
NIGMSLogoS JHULogoS JHUSOMLogoS2