The Goley Lab is part of the Department of Biological Chemistry at the Johns Hopkins University School of Medicine in Baltimore, MD. We are a bacterial cell biology lab broadly interested in understanding how bacterial cells grow and divide with regularity and accuracy. We use cell biological, biochemical, genetic, and structural approaches to dissect cellular processes with the aim of understanding how they work in molecular detail. A detailed understanding of the fundamental mechanisms of bacterial growth is required to confront the growing crisis in antibacterial resistance. We get really excited about our research.

The Goley Lab recognizes that to do our best and most creative science, we need to include individuals with diverse perspectives, identities, and life experiences. We maintain a safe, inclusive, and equitable lab environment, and we respect and celebrate diversity in all its forms. Erin is committed to individualized and intentional mentoring for all lab members.

We respectfully acknowledge that Johns Hopkins University is located on unceded lands of the Piscataway and Susquehannock Peoples.
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Latest News
Jan 2023: BCMB student Barbara Talavera joined us for her third rotation. Welcome, Barbara!
Jan 2023
: Jordan's awesome review on the development of Caulobacter as a model system is out!
Jan 2023: Allison's work on OPGs in Caulobacter is out in Current Biology. Check out this nice dispatch on her work from Tobias Dörr.
Dec 2022
: Wanda pre-print describing methods she developed to investigate the cell biology of the obligate intracellular pathogen, Rickettsia parkeri is posted on bioRxiv. Check it out here.
Nov 2022:
Chris's thesis work is out in pre-print form. Learn all about how constriction is activated in concert with chromosome segregation in Caulobacter here.
Nov 2022:
1st year GPBC student Austin Dabbs joined us for his second rotation. Happy to have you, Austin.
Sept 2022:
1st year GPBC student Piyusha Mongia joined us for her first rotation. Welcome Piyusha!
May 2022:
Both Allison and Chris are PhinisheD, and Ashley graduated with her bachelors. Allison will start a postdoc at the Applied Physics Lab, Chris will be a Senior Associate at Milken Institute, and Ashley is heading to the Broad for a research associate position. Congrats to all - we'll miss you so much!
Apr 2022:
Allison's work on the role of EstG in promoting envelope integrity is now pre-printed! Check it out here.
Mar 2022
: BCMB student Dezmond Cole joined the lab for his thesis research!
Feb 2022:
BCMB first year Marissa Feeley joined us for the 3rd rotation. Welcome, Marissa!
Dec 2021:
BCMB first year Dezmond Cole joined us for the second rotation. Happy to have you, Dezmond!
Sept 2021:
BCMB first year Joshua Garcia-Colon joined the lab for his first rotation! Welcome Josh!
May 2021:
BCMB student Trung Nguyen joined the lab for his thesis work! We're happy to have you, Trung!
Apr 2021:
BCMB student Isaac Payne joined the lab for his thesis work! Welcome aboard Isaac!
Mar 2021: The lab was awarded an R21 from the NIAID to establish methods to quantitatively analyze growth of the obligate intracellular pathogen Rickettsia parkeri!
Jan 2021:
BCMB 1st year Trung Nguyen joined us for his second rotation. Welcome Trung!
Oct 2020:
Jordan and Erika made the lab proud with talks at CauloCon 2.0!
Oct 2020:
Jordan’s review on FtsZ dynamics was accepted in Current Opinion in Cell Biology. Congrats Jordan!
Oct 2020:
Allison’s review on our evolving understanding of peptidoglycan synthesis came out in Current Biology! Congrats Allison!
Sept 2020: BCMB first year Isaac Payne joined the lab for his first rotation. Welcome, Isaac!
Aug 2020:
Chris gave a great talk at the Young Microbiologists Symposium hosted by University of Southhampton! Congrats Chris!

Selected Recent Publications
CdnL

The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter (2020) PLOS Genetics
FzlAsummary
An essential regulator of bacterial division links FtsZ to cell wall synthase activation (2019) Curr Biol

FzlAGraphAbs
An FtsZ-binding protein regulates the rate of constriction during Caulobacter cell division.
Lariviere et al (2018) Mol Micro
SLBGraphAbs
FtsZ assembles into species- and disordered linker-dependent superstructures on membranes in vitro.
Sundararajan et al (2018) Mol Micro

Funding
NIGMSLogoS NIAIDsmall JHULogoS JHUSOMLogoS2