The Goley Lab is part of the Department of Biological Chemistry at the Johns Hopkins University School of Medicine in Baltimore, MD. We are a bacterial cell biology lab broadly interested in understanding how bacterial cells grow and divide with regularity and accuracy. We use cell biological, biochemical, genetic, and structural approaches to dissect cellular processes with the aim of understanding how they work in molecular detail. A detailed understanding of the fundamental mechanisms of bacterial growth is required to confront the growing crisis in antibacterial resistance. We get really excited about our research.

Johns Hopkins University School of Medicine
Latest News
n 2019: BCMB first year Chad Hicks joined us for his second rotation. Welcome, Chad!
Oct 2018: PJ’s latest work on FzlA-dependent activation of FtsWI-mediated PG synthesis for division is now on bioRxiv!
Sept 2018:
BCMB student Marie Stoltzfus joined us for her first rotation. Welcome, Marie!
Sept 2018: Our collaboration with Pam Brown’s lab on Agrobacterium FtsZs is out as a pre-print on bioRxiv.
July 2018:
Kousik’s paper on FtsZ assembly dynamics on membranes was accepted at Mol Micro!
June 2018
: High school students Olivia Robinson and Brandon King have joined us for summer research!
May 2018: We started a Slack group for the Caulobacter community (and friends). Message Erin for an invitation.
May 2018: Jordan Barrows joined the lab for his thesis work! Welcome back, Jordan!
May 10, 2018: Our latest swarmer has moved on… Kousik will begin his postdoc in Aaron Straight’s lab at Stanford. We’ll miss you Kousik!

Selected Recent Publications
FtsZ assembles into species- and disordered linker-dependent superstructures on membranes in vitro.
Sundararajan et al (2018) Mol Micro

An FtsZ-binding protein regulates the rate of constriction during Caulobacter cell division.
Lariviere et al (2018) Mol Micro

FtsEX links FtsZ to cell wall hydrolysis pathways to promote late stages of cell division.
Meier et al (2017) PLoS Genetics

The disordered linker of FtsZ regulates its assembly dynamics and superstructure.
Sundararajan (2017) JBC