Polarity
Seydoux, G. 'Goldilocks' suppressor screens identifies web of polarity regulators. Nature Cell Biology, 2012, 2012, 15(1):9-10. doi:10.1038/ncb2666. [PDF reprint]
Motegi, F., Zonies, S., Hao, Y., Cuenca, A., Griffin, E., Seydoux, G. (2011) Microtubules induce self-organization of polarized PAR domains in C. elegans zygotes, Nature Cell Biology, Oct 9. doi: 10.1038/ncb2354 [PDF reprint]
Griffin, E., Odde, D., Seydoux, G. (2011) Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle. Cell, 2011 Sep 16;146(6):955-68. [PDF reprint]
Zonies, S., Motegi, F., Hao, Y., Seydoux, G (2010). Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2. Development, 137(10):1669-77. [PDF reprint]
Cheng K. , Klancer R. , Singson A, and Seydoux. (2009) Regulation of MBK-2/DYRK by CDK-1 and the pseudo-phosphatases EGG-4 and EGG-5 during the
oocyte-to-embryo transition. Cell, 139(3):560-72. [PDF reprint]
Motegi, F. and Seydoux, G. (2007). Revisiting the role of microtubules in C. elegans polarity. JCB 179:367-9. [PDF reprint]
Hao, Y., Boyd, L., Seydoux, G. (2006). Stabilization of
cell polarity by the RING protein PAR-2. Developmental
Cell 10, 199208. [PDF
reprint] [Supplemental
Data]
Seydoux, G. (2004) Surfing the actomyosin wave: polarization
of the C. elegans zygote. Developmental Cell
7, 285-286. [PDF reprint]
Pellettieri, J., Reinke, V. , Kim, S. K. and Seydoux, G.
(2003) Coordinate activation of maternal protein degradation
during the Egg-to-Embryo Transition in C. elegans.
Developmental Cell 5, 451–462. [PDF
reprint]
Cuenca, A., Schetter A. , Aceto D., Kemphues K., Seydoux,
G. (2003). Polarization of the C. elegans zygote proceeds
via distinct establishment and maintenance phases. Development
130, 1255-1265. [PDF reprint]
Pellettieri and Seydoux (2002). Anterior/Posterior Polarity
in Worms and Flies – PARallels and Differences. Science,
298:1946-50. [PDF
reprint]
Wallenfang, M. R., and Seydoux, G. (2000). Polarization of
the anterior-posterior axis of C. elegans is a microtubule-directed
process. Nature 408, 89-92. [PDF
reprint]
Germline
Wang, J. and Seydoux, G. (2012). Germ cell specification. Book Chapter In Germline development in C. elegans. Adv Exp Med Biol. 2013;757:17-39. doi: 10.1007/978-1-4614-4015-4_2. [PDF reprint]
Voronina E, Paix A, Seydoux G. The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells. Development. 2012 Oct;139(20):3732-40. [PDF reprint]
Voronina, E, Seydoux, G, Sassone-Corsi, P, Nagamori, I. 2011. RNA granules in the germline. CSH Perspectives, Editors: Paolo Sassone-Corsi, Margaret T. Fuller, and Robert Braun, Dec 1;3(12). pii: a002774. doi:10.1101/cshperspect.a002774. [PDF reprint]
Gallo, C, Wang, J. Motegi, F., Seydoux, G. (2010). Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans. Science. [Abstract]
Voronina, E, Seydoux, G (2010), The nucleoporin NPP-10/Nup98 is required for the integrity and function of germline P granules. Development 137, 1441-1450. [PDF reprint]
Christopher Merritt, Christopher M. Gallo, Dominique Rasoloson, and Geraldine Seydoux (2010). Transgenic solutions for the germline. ed. The C. elegans Research Community, WormBook. [online]
Merritt, C., Seydoux, G (2010). The Puf RNA-binding Proteins FBF-1 and FBF-2 Inhibit the Expression of Synaptonemal Complex Proteins in Germline Stem Cells. Development, 137(11):1787-98. [PDF reprint]
Merritt C., Rasoloson D., Ko D., Seydoux G (2008). 31; UTRs are the primary regulators of gene expression in the C. elegans germline. Current Biology,
18(19):1476-82. [PDF reprint]
Nakamura, A and Seydoux, G. (2008). Less is more: specification of the
germline by transcriptional repression. Development, 135(23):3817-27. [PDF reprint]
Gallo C., Munro, E., Rasoloson D., Merritt, C, and Seydoux G. (2008). Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos. Developmental Biology, 323 (1): 76–87. [PDF reprint]
Ghosh, D., Seydoux, G. (2008). Inhibition of transcription by the C. elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation. Genetics, 178(1):235-43. [PDF
reprint]
Stitzel, M., Cheng, K. , Seydoux, G. (2007). Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition. Current Biology, 179:367-9. [PDF
reprint] [Supplemental Data]
Stitzel, M. and Seydoux, G (2007). Regulation of the oocyte-to-zygote transition. Science, 316(5823):407-8. [Abstract] [Full text]
Seydoux, G and Braun, R. (2006). Pathway to totipotency: lessons from germ cells. Cell 127, 891-904. [PDF
reprint]
Gallo CM, Seydoux G (2006). Toti"potent" repressors. Bioessays. 28(9):865-867 [PDF
reprint]
Ingrid D¹Agostino, Chris Merritt, Pei-Lung Chen, Geraldine
Seydoux and Kuppuswamy Subramaniam (2006). Translational
repression restricts expression of the C. elegans Nanos
homolog NOS-2 to the embryonic germline. Developmental
Biology 292 244252. [PDF
reprint]
Stitzel, M., Pellettieri, M. and Seydoux, G (2006) The
C. elegans DYRK kinase MBK-2 marks oocyte proteins
for degradation in response to meiotic maturation. Current
Biology 16, 17. [PDF
reprint] [Supplemental Material]
DeRenzo, C. and Seydoux, G. (2004) A clean start: coordinate
degradation of maternal proteins at the egg-to-embryo transition.
Trends in Cell Biology 14, 420-428. [PDF
reprint]
DeRenzo, C., Reese, K. and Seydoux, G. (2003). Exclusion
of germ plasm proteins from somatic lineages by cullin-dependent
degradation. Nature 424, 685-9. [PDF
reprint]
Subramaniam, K. and Seydoux, G. (2003). Dedifferentiation
of primary spermatocytes into germ cell tumors in C. elegans
lacking the Pumilio-like protein PUF-8. Current Biology
13, 134-139. [PDF reprint]
Tenenhaus, C., Subramaniam, K., Dunn, M. Seydoux, G. (2001).
PIE-1 is a bifunctional protein that regulates maternal and
zygotic gene expression in the embryonic germ lineage of C.
elegans. Genes and Development 15, 1031-1040. [PDF
reprint]
Reese, K. J., Dunn, M. A., Waddle J. A. and Seydoux, G. (2000).
Asymmetric segregation of PIE-1 in C. elegans is mediated
by two complementary mechanisms that act through separate
PIE-1 protein domains. Molecular Cell 6, 445-455. [PDF
reprint]
Seydoux G., and Schedl, T. (2000). The germline in C. elegans:
Origins, Proliferation and Silencing. In “Establishment
of Cell Lineages and Patterning of the Embryo”, a book
in the International Review of Cytology Series edited by Etkin
and Jeon.
Subramaniam, K. and Seydoux, G. (1999). nos-1 and nos-2,
two genes related to Drosophila nanos, regulate primordial
germ cell development and survival in C. elegans. Development
126, 4861-4871. [PDF reprint]
Batchelder, C., Dunn, M. A., Choy, B., Suh, Y., Cassie,
C., Shim, E. Y., Shin, T. H., Mello, C., Seydoux, G., Blackwell,
T. K. (1999) Transcriptional repression by the Caenorhabditis
elegans germ-line protein PIE-1. Genes and Development
13(2):202-12.
Seydoux, G. and Strome S. (1999). Launching the germline
in C. elegans: regulation of gene expression in early
germ cells. Development 126, 3275-3283. [PDF
reprint]
Tenenhaus, C., Schubert, C., Seydoux, G. (1998). Genetic
requirements for PIE-1 localization and inhibition of gene
expression in the embryonic germ lineage of Caenorhabditis
elegans. Developmental Biology , 200(2):212-24.
[PDF reprint]
Seydoux, G. and Dunn, M. (1997). Transcriptionally-repressed
germ cells lack a subpopulation of phosphorylated RNA polymerase
II in early embryos of C. elegans and D. melanogaster.
Development 124, 2191-2201. [PDF
reprint]
Seydoux, G., Mello, C. C., Pettitt, J., Wood, W., Priess,
J., Fire, A. (1996). Repression of gene expression in the
embryonic germ lineage of C. elegans. Nature
382, 713-716.
Other
Seydoux, G (2006) The 2006 GSA medal-Victor Ambros. Genetics, 172(2):721-2. [PDF reprint]
Wallenfang, M. R., and Seydoux, G. (2002). cdk-7 is required
for mRNA transcription and cell cycle progression in C.
elegans embryos. Proc. Nat. Acad. Sci. 99, 5527-5532.
[PDF reprint]
Strome, S. , Powers, J., Dunn, M., Reese, K., Seydoux, G
and Saxton, W. (2001). Spindle dynamics and the role of gamma-tubulin
in early C. elegans embryos. Mol. Biology of the
Cell 12, 1751-64. [PDF
reprint]
Golden A., Sadler P. L, Wallenfang, M. R., Schumacher J.
M, Hamill, Bates G., Bowerman B., Seydoux, G., and Shakes,
D. C. (2000) Metaphase to anaphase transition defective (mat)
mutants in Caenorhabditis elegans. Journal of Cell
Biology 151, 1469-1482. [PDF
reprint]
Prasad, B. C., Ye, B., Zackhary, R., Schrader, K., Seydoux,
G., Reed, R. R. (1998). unc-3, a gene required for axonal
guidance in Caenorhabditis elegans, encodes a member
of the O/E family of transcription factors. Development,
125(8):1561-8
Halpern, M. and Seydoux, G. (2000). Embryo emergent: Elucidating
the cell biology of development. Embo Reports 1, 469-472.
[PDF reprint]
Seydoux, G. (1996). Mechanisms of translational control in
early development. Current Opinion in Genetics and Development
6, 555-561.
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