Craig, N.L., Section Editor; W. Lennarz, M. Lane, Editors (in preparation). Encyclopedia of Biological Chemistry, 2/e Elsevier Inc.

Craig, N.L., O. Cohen-Fix, C. Greider, R. Green, G. Storz, C. Wolberger (2010). Molecular Biology: Principles of Genome Function, Oxford University Press.

Craig, N.L., R. Craigie, M. Gellert, A. Lambowitz, Editors (2002) Mobile DNA II. American Society for Microbiology, Washington D.C.

Peer Reviewed Manuscripts

Mitra,R., Li, X., Kapusta, A., Mayhew, D., Mitra, R.D., Feschotte, C., Craig, N.L. (2013) Functional characterization of piggyBat from the bat Myotis lucifugus unveils an active mammalian DNA transposon. Proc. Nat’l Acad. Sci. U.S.A. 110(1):234-239 PMID: 23248290; PMCID: PMC3538221. Article
Woodard, L.E., Li, X, Malani, N., Kaja, A., Hice, R.H., Atkinson, P.W., Bushman, F.D., Craig, N.L., Wilson, M.H. (2012) Comparative analysis of the recently discovered hAT transposon TcBuster in human cells. PLoS ONE 7(11):e42666. Epub 2012 Nov 15.  PMID:23166581; PMCID: PMC3499496. Article
Hencken, C.G., Li, X., Craig, N.L. (2012) Functional characterization of an active Rag-like transposase.. Nature Structural and Molecular Biology 19(8):834-836.  PMID: 22773102; PMCID: PMC3414642. Article
Burnight, E.R., Staber, J.M., Korsakov, P., Li, X., Brett, B.T., Scheetz, T.E., Craig, N.L., McCray, P.B. Jr. (2012) A hyperactive transposase promotes persistent gene transfer of a piggyBac DNA transposon. Molecular Therapy-Nucleic Acids 1, e50 PMID: 23344650; PMCID: PMC3499692. Article
Li, X., Ewis, H., Hice, R.H., Malani, N., Parker, N., Zhou, L., Feschotte, C., Bushman, F.D., Atkinson, P.W., Craig, N.L. (2012) A resurrected mammalian hAT transposable element and a closely related insect element are highly active in human cell culture. PNAS Early Edition Oct. 22.  PMID:23091042; PMCID: PMC3568352. Article
Green, B., Bouchier, C., Fairhead, C., Craig, N.L., Cormack, B.P. (2012) Insertion site preference of Mu, Tn5, and Tn7 transposons. Mobile DNA 3(1):3.  PMCID: PMC3292447. Article
Arensburger, P., Hice, R.H., Wright, J.A., Craig, N.L., Atkinson, P.W. (2011) The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs. BMC Genomics 12:606.  PMCID: PMC3259105. Article
Doherty, J.E., Huye, L., Yusa, K., Zhou, L., Craig, NL. Wilson, M. (2011) Hyperactive piggyBac gene transfer in human cells and in vivo. Hum Gene Ther (Epub ahead of print) 23(3):311-320 PMCID: PMC3300075. Article
Li, M.A., Turner, D., Ning, Z., Yusa, K., Liang, Q., Eckert, S., Rad, L., Fitzgerald, T., Craig, N.L., Bradley, A. (2011) Mobilization of giant piggyBac transposons in the mouse genome. Nucleic Acids Res 39:e148 PMCID: PMC3239208. Article
Arensburger, P., Hice, R.H., Zhou, L, Smith, R.C., Tom, A.C., Wright, J.A., Knapp, J., O'Brochta, D.A., Craig, N.L., Atkinson, P.W. (2011) Phylogenetic and functional characterization of the hAT transposon superfamily. Genetics. May;188(1):45-57. Epub 2011 Mar 2. PMCID: PMC3120152. Article

Yusa, K., L. Zhou, M.A. Li, A. Bradley, N.L. Craig (2011) A hyperactive piggyBac transposase for mammalian applications. Proc Natl Acad Sci USA Early Edition 1/4/11 PMID: 21205896 PMCID: PMC3029773. Article

Gangadharan, S., L. Mularoni, J. Fain-Thornton, S.J. Wheelan, N.L. Craig (2010) DNA transposon Hermes inserts into DNA in nucleosome-free regions in vivo. Proc Natl Acad Sci USA 107:21966-21972 PMID: 21131571 PMCID: PMC3009821. Article

Mitra, R., G.J. McKenzie, L. Yi, C.A. Lee, N.L. Craig (2010) Characterization of the TnsD-attTn7 complex that promotes site-specific insertion of Tn7. Mobile DNA 1:18 PMID: 20653944 PMCID: PMC2918618. Article

Holder, J.W., N.L. Craig (2010) Architecture of the Tn7 Post-Transposition Complex: an elaborate nucleoprotein structure. J Mol BIol 401:167-181. PMCID: PMC2927125. Article

Ray, D.A., C. Feschotte, H.J.T. Pagan, J.D. Smith, E. Pritham, P. Arensburger, P.W. Atkinson, N.L. Craig (2008) Multiple waves of recent DNA transposon activity in the bat, Myotis lucifugus Genome Research 18:717-728. PMCID: PMC2336803. Article

Mitra, R., J. Fain-Thornton, N.L. Craig (2008) piggyBac can bypass DNA synthesis during cut and paste transposition. EMBO J 27:1097-1109. PMCID: PMC2323262. Article

Evertts, A.G., C. Plymire, N.L. Craig, H.L. Levin (2007) The Hermes transposon of Musca domestica is an efficient tool for the mutagenesis of Schizosaccharomyces pombe. Genetics 177:2519-2523. PMCID: PMC2219505. Article

McKenzie, G.J., N.L. Craig (2006) Fast, easy and efficient: site-specific insertion of transgenes into Enterobacterial chromosomes using Tn7 without need for selection of the insertion event. BMC Microbiol 6:39. PMCID: PMC1475584. Article

Hickman, A.B., Z.N. Perez, L. Zhou, P. Musingarimi, R. Ghirlando, J.E. Hinshaw, N.L. Craig, F. Dyda (2005) Molecular architecture of a eukaryotic DNA transposase. Nat Struct Mol Biol 12:715-721. PMID: 16041385. Article

Perez, Z.N., P. Musingarimi, N.L. Craig, F. Dyda, A.B. Hickman (2005) Purification, crystallization and preliminary crystallographic analysis of the Hermes transposase. Acta Crystallogr Sect F Struct Biol Crys Commun 61:587-590. PMCID: 1952326. Article

Kuduvalli, P.N., R. Mitra, N.L. Craig (2005) Site-specific Tn7 Transposition into the Human Genome. Nucleic Acids Res 33:857-863. PMCID: PMC549396. Article

Ferguson, S.B., E.S. Anderson, R.B. Harshaw, T. Thate, N.L. Craig, H.C. Nelson (2005) Protein Kinase A Regulates Constitutive Expression of Small Heat Shock Genes in an Msn2p/4p-Independent and Hsf1p-Dependent Manner in Saccharomyces cerevisiae. Genetics 169:1203-1214. PMCID: PMC1449542. Article

Zhou, L., R. Mitra, P.W. Atkinson, A.B. Hickman, F. Dyda, N.L. Craig (2004) Transposition of hAT elements links transposable elements and V(D)J recombination. Nature 432:995-1001. PMID: 15616554. Article

Kumar, A, M. Seringhaus, M.C. Biery, R.J. Sarnovsky, L. Umansky, S. Piccirillo, M. Heidtman, K.H Cheung, C.J. Dobry, M.B. Gerstein, N.L. Craig, M. Snyder (2004) Large-scale mutagenesis of the yeast genome using a Tn7-derived multipurpose transposon. Genome Res 14:1975-1986. PMCID: PMC524422. Article

Ronning, D.R., Li, Y., Perez, Z.N., Ross, P.D., Hickman, A.B., Craig, N.L., Dyda, F. (2004) The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA. EMBO J 23:2972-2981. PMCID: PMC514928. Article

Castano, I., R. Kaur, S. Pan, R. Cregg, A. De Las Penas, N. Guo, M.C. Biery, N.L. Craig, B.P. Cormack (2003) Tn7-based Genome-wide Random Insertional Mutagenesis of Candida glabrata. Genome Res 13:905-915. PMCID: PMC430877. Article

Skelding, Z., J. Queen-Baker, N.L. Craig (2003) Alternative Interactions between the Tn7 Transposase and the Tn7 Target DNA Binding Protein Regulate Target Immunity and Transposition. EMBO J 22:5904-5917. PMCID: PMC275408. Article

Uhl, M.A., M. Biery, N. Craig, A.D. Johnson (2003) Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C. albicans. EMBO J 22:2668-2678. PMCID: PMC156753. Article

Peters, J.E., T.E. Thate, N.L. Craig (2003) Definition of the Escherichia coli MC4100 Genome by Use of a DNA Array. J Bact 185(6):2017-2021. PMCID: PMC150127. Article

Skelding, Z., R. Sarnovsky, N.L. Craig (2002) Formation of a nucleoprotein complex containing Tn7 and its target DNA regulates transposition initiation. EMBO J 21:3494-3504. PMCID: PMC126096. Article

Bachman, N., M. Biery, J.D. Boeke, N.L. Craig (2002) Tn7-mediated mutagenesis of Saccharomyces cerevisiase genomic DNA in vitro. Methods in Enzymology 350:230-247. PMID: 12073315

Rao, J.E., N.L. Craig (2001) Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7. J Mol Biol 307:1161-1170. PMID: 11292332. Article

Peters, J.E., N.L. Craig (2001) Tn7 recognizes target structures associated with DNA replication using the DNA binding protein TnsE. Genes Dev 15:737-747. PMCID: PMC312648. Article

Kuduvalli, P.N., J.E. Rao, N.L. Craig (2001) Target DNA Structure Plays a Critical Role in Tn7 Transposition. EMBO J 20:924-932. PMCID: PMC145423. Article

Stellwagen, A.E., N.L. Craig (2001) Analysis of Gain of Function Mutants of an ATP-dependent Regulator of Tn7 Transposition. J Mol Biol 305:633-642. PMID: 11152618. Article

Peters, J.E., N.L. Craig (2000) Tn7 transposes proximal to DNA double-strand breaks and into regions where chromosomal DNA replication terminates. Mol Cell 6:573-582. PMID: 11030337. Article

Hickman, A.B., Y. Li, S.V. Mathew, E.W. May, N.L. Craig, F. Dyda (2000) Unexpected Structural Diversity in DNA Recombination: The Restriction Endonuclease Connection. Molecular Cell 5:1025-1034. PMID: 10911996. Article

Lu, F., N.L. Craig (2000) Isolation and characterization of Tn7 transposase gain-of-function mutants: a model for transposase activation. EMBO J 19:3446-3457. PMCID: PMC313929. Article

DeBoy, R.T., N.L. Craig (2000) Target Site Selection by Tn7: attTn7 Transcription and Target Activity. J Bacteriol 182:3310-3313. PMCID: PMC94526. Article

Rao, J.E., P.E. Miller, N.L. Craig (2000) Recognition of triple-helical DNA structures by transposonTn7. Proc Natl Acad Sci USA 97:3936-3941. PMCID: PMC18120. Article

Biery, M.C., M. Lopata, N.L. Craig (2000) A Minimal System for Tn7 Transposition: The Transposon-encoded Proteins TnsA and TnsB can execute DNA breakage and joining reactions that generate circularized Tn7 species. J Mol Biol 297:25-37. PMID: 10704304. Article

Biery, M.C., F.J. Steward, A.E. Stellwagen, E.A. Raleigh, N.L. Craig (2000) A Simple in vitro Tn7-based Transposition System with Low Target Site Selectivity for Genome and Gene Analysis. Nucleic Acids Res 28:1067-1077. PMCID: PMC102592. Article

Sharpe, P.L., N.L. Craig (1998) Host Proteins can Stimulate Tn7 Transposition: A Novel Role for the Ribosomal Protein L29 and the Acyl Carrier Protein. EMBO J 17:5822-5831. PMCID: PMC1170910. Article

Oppon, J.C., R.J. Sarnovsky, N.L. Craig, D.E. Rawlings (1998) A Tn7-like transposon is present in the glmUS region of the obligately chemoautolithotrophic bacterium Thiobacillus ferrooxidans. J Bacteriol 180: 3007-3012. PMCID: PMC107274. Article

Stellwagen, A.E., N.L. Craig (1997) Avoiding Self: Two Tn7-encoded proteins mediate target immunity in Tn7 transposition. EMBO J 16:6823-6834. PMCID: PMC1170286. Article

Gwinn, M.L., A.E. Stellwagen, N.L. Craig, J.-F. Tomb, H.O. Smith (1997) in vitro Tn7 Mutagenesis of Haemophilus influenzae Rd and Characterization of the Role of atpA in Transformation. J Bacteriol 179:7315-7320. PMCID: PMC179681. Article

Stellwagen, A.E., N.L. Craig (1997) Gain-of-Function Mutations in TnsC, an ATP-Dependent Transposition Protein that Activates the Bacterial Transposon Tn7. Genetics 145:573-585. PMCID: PMC1207843. Article

DeBoy, R.T., N.L. Craig (1996) Tn7 transposition as a probe of cis-interactions between widely separated (190 Kilobases apart) DNA sites in the Escherichia coli chromosome. J Bacteriol 178:6184-6191. PMCID: PMC178488. Article

Sarnovsky, R., E.W. May, N.L. Craig (1996) The Tn7 Transposase is a Heteromeric Complex in which DNA Breakage and Joining Activities are Distributed Between Different Gene Products. EMBO J 15:6348-6361. PMCID: PMC452457. Article

Wolkow, C.A., R.T. DeBoy, N.L. Craig (1996) Conjugating Plasmids are Preferred Targets for Tn7. Genes Dev 10:2145-2157. PMID: 8804309. Article

May, E.W., N.L. Craig (1996) Switching from cut-and-paste to replicative Tn7 transposition. Science 272:401-404. PMID: 8602527. Abstract

Gary, P.A., M.C. Biery, R.J. Bainton, N.L. Craig (1996) Multiple DNA processing reactions underlie Tn7 transposition. J Mol Biol 257:301-316. PMID: 8609625. Article

Bainton, R., K. Kubo, J.-N. Feng and N.L. Craig (1993) Tn7 Transposition: Target DNA recognition is mediated by multiple Tn7-encoded proteins in a purified in vitro system. Cell 72:931-943. PMID 8384534. Article

Tower, J., G.H. Karpen, N.L. Craig and A.C. Spradling (1993) Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics 133: 347-359. PMCID: PMC1205324. Article

Hagemann, A. and N.L. Craig (1993) Tn7 transposition creates a hotspot for homologous recombination at the transposon donor site. Genetics 133:9-16. PMCID: PMC1205302. Article

Gamas, P. and N.L. Craig (1992) Purification and characterization of TnsC, a Tn7 transposition protein that binds ATP and DNA. Nucleic Acids Res 10:2525-2532. PMCID: PMC312388. Article

Arciszewska, L. and N.L. Craig (1991) Interaction of the Tn7-encoded protein TnsB with the ends of the transposon. Nucleic Acids Res 19:5021-5029. PMCID: PMC328805. Article

Arciszewska, L., R.L. McKown and N.L. Craig (1991) Purification of TnsB, a Transposition Protein That Binds to the Ends of Tn7. J Biol Chem 266:21736-21744. PMID: 1657979. Article

Orle, K.A. and N.L. Craig (1991) Identification of transposition proteins encoded by the bacterial transposon Tn7. Gene 104:125-131. PMID: 1655576. Article

Bainton, R., P. Gamas, and N.L. Craig (1991) Tn7 Transposition in vitro Proceeds through an Excised Transposon Intermediate Generated by Staggered Breaks in DNA. Cell 65:805-816. PMID: 1645619. Article

Kubo, K. and N.L. Craig (1990) Bacterial Transposon Tn7 Utilizes Two Different Classes of Target Sites. J Bacteriol 172:2774-2778. PMCID: PMC208925. Article

Waddell, C. and N.L. Craig (1989) Tn7 Transposition: Recognition of the attTn7 target sequence. Proc Natl Acad Sci USA 86:3958-3962. PMCID: PMC287367. Article

Arciszewska, L., D. Drake and N.L. Craig (1989) Transposon Tn7: cis-acting Sequences in Transposition and Transposition Immunity. J Mol Biol 207:35-52. PMID: 2544738. Article

Gringauz, E., K. Orle, C. Waddell and N.L. Craig (1988) Recognition of Escherichia coli attTn7 by Transposon Tn7: Lack of Specific Sequence Requirements at the Point of Tn7 Insertion. J Bacteriol 170:2832-2840. PMCID: PMC211210. Article

Waddell, C. and N.L. Craig (1988) Tn7 Transposition: Two Transposition Pathways Directed by Five Tn7-encoded Genes. Genes Devel 2:137-149. PMID: 2834269. Article

McKown, R., K. Orle, T. Chen and N.L. Craig (1988) Sequence Requirements of Escherichia coli attTn7, a Specific Site of Transposon Tn7 Insertion. J Bacteriol 170:352-358. PMCID: PMC210649. Article

McKown, R., C. Waddell, L. Arciszewska and N.L. Craig (1987) Identification of a Transposon Tn7-Dependent DNA Binding Activity that Recognizes the Ends of Tn7. Proc Natl Acad Sci USA 84:7807-7811. PMCID: PMC299398. Article

Craig, N.L. and H.A. Nash (1984) E. coli integration host factor binds to specific sites in DNA. Cell 39:707-716. PMID: 6096022. Article

Craig, N.L. and H.A. Nash (1983) The mechanism of phage lambda site-specific recombination: Site-specific breakage of DNA by Int topoisomerase. Cell 35:795-803. PMID: 6317202. Article

Craig, N.L. and J.W. Roberts (1981) Function of nucleotide triphosphate and polynucleotide in Escherichia coli RecA protein-directed cleavage of phage lambda repressor. J Biol Chem 256:8039-80444. PMID: 6455420. Abstract

Craig, N.L. and J.W. Roberts (1980) E. coli RecA protein-directed cleavage of phage lambda repressor requires polynucleotide. Nature 283:26-30. PMID: 6444245. Abstract

Roberts, J.W., C. W. Roberts, N.L. Craig and E.M. Phizicky (1979) Activity of the Escherichia coli recA gene product. Cold Spring Harbor Symp Quant Biol 43:917-920. PMID: 158477.

Roberts, J.W., C. W. Roberts, and N.L. Craig (1978) The Escherichia coli recA gene product inactivates phage lambda repressor. Proc Natl Acad Sci USA 75:4714-4718. PMCID: PMC336190. Article

Invited Reviews, Book Chapters and Letters

Craig NL, Eickbush TH, Voytas DF (2010) Welcome to Mobile DNA. Mob DNA 1(1):1 PMID: 20226071, PMCID: PMC2836004

Chaconas G, Craig N, Curcio MJ, Deininger P, Feschotte C, Levin H, Rice PA, Voytas DF (2010) Meeting Report for Mobile DNA 2010. Mob DNA 1(1):20. PMID: 20735816

Atkinson, P.W., D.A. O'Brochta, N.L. Craig (2007) The hobo, Hermes and Herves Transposable Elements of Insects. In Area-wide control of insect pests: From Research to Field Implementation (Vreysen, M.J.B., A.S. Robinson, J. Hendrichs, eds.) The Netherlands

Segall, A.M., N.L. Craig (2005) New wrinkles and folds in site-specific recombination. Mol Cell 19:433-435. PMID: 16109368

Craig, N.L. (2002) Tn7. In Mobile DNA II, (Craig, N.L., R. Craigie, M. Gellert, A. Lambowitz, ed.) ASM Press, Washington, D.C. pp. 423-454

Craig, N.L. (2002) Mobile DNA: an Introduction. In Mobile DNA II, (Craig, N.L., R. Craigie, M. Gellert, A. Lambowitz, ed.) ASM Press, Washington, D.C. pp. 3-11

Craig, N.L. (2002) Transposases and Integrases. Encyclopedia of Life Sciences (Macmillan Reference Ltd.)

Peters, J.E., N.L. Craig (2001) Tn7: Smarter Than We Thought. Nat Rev Mol Cell Biol 2:806-814. PMID: 11715047

Craig, N.L. (1999) in Encyclopedia of Molecular Biology (ed. Thomas E. Creighton), London, England. Autonomous Controlling Elements, pp. 222-223; Controlling Elements, pp. 575-576; Hybrid Dysgenesis, pp. 1175-1176; Immunity, Transposon, pp. 1220-1221; Insertion Sequence Elements, pp. 1266-1267; Inverted Terminal Repeat, pp. 1310-1311; Jumping Gene, pp 1332-1333; Mobile Element, pp. 1520-1521; Mu Phage, pp. 1547-1548; Nonautonomous Controlling Elements, pp. 1630; P Elements, pp. 1743; Retrotransposons, pp. 2148-2149; Transposable Elements, pp. 2650-2652; Transposase, pp. 2652-2653; Transposition, pp. 2653-2654;Transposon, pp. 2654-2655; Ty Elements, pp. 2705;

Stellwagen, A.E., N.L. Craig (1998) Mobile DNA elements: controlling transposition with ATP-dependent molecular switches. Trends Biochem Sci 23:486-490. PMID: 9868372

Roth, D.B., N.L. Craig (1998) VDJ Recombination: A Transposase Goes to Work. Cell 94:411-414. PMID: 9727482

Craig, N.L. (1997) Target Site Selection in Transposition. Annu Rev Biochem 66:437-474. PMID: 9242914

Craig, N.L. (1996) V(D)J Recombination and Transposition: Closer Than Expected. Science 271:1512. PMID: 8599105

Craig, N.L. (1996) Transposition. In: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology II (eds. Neidhardt, F. et al) American Society for Microbiology, Washington, D.C., pp. 2339-2362

Craig, N.L. (1996) Transposon Tn7. Curr Top in Microbiol Immunol 204:27-48. PMID: 8556868

Craig, N.L. (1991) Understanding how transcriptional enhancers work. Curr Biol 1:100-102. PMID: 15336178 Craig, N.L. (1995) Unity in transposition reactions. Science 270:253-254. PMID: 7569973

Craig, N.L. (1991) Tn7: a target site-specific transposon. Mol Microbiol 5:2569-2573. PMID: 1664019

Craig, N.L. (1990) P Element Transposition. Cell 62:399-402. PMID: 2165863

Craig, N.L. (1989) Transposon Tn7. In: Mobile DNA (ed. D. Berg and M. Howe), American Society for Microbiology, Washington, DC, pp. 211-225 Craig, N.L. (1990) P Element Transposition. Cell 62:399-402. PMID: 2165863

Craig, N.L. (1988) The Mechanism of Conservative Site-Specific Recombination. Annu Rev Genet 22:77-105. PMID: 3071260

Craig, N.L. and N. Kleckner (1987) Transposition and site-specific recombination. In: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology (eds. Neidhardt, F., J. Ingraham, K. Low, B. Magasanik, M. Schaechter and M. Umbarger), American Society for Microbiology, Washington, D.C. pp. 1054-1070

Craig, N.L. (1984) Site-specific inversion: enhancers, recombination proteins and mechanism. Cell 41:649-650. PMID: 2988781

Craig, N.L. (1984) DNA recombination: Resolution of intermediates. Nature 311:706-707. PMID: 6387505

Craig, N.L. and H.A. Nash (1983) The mechanism of phage lambda site-specific recombination: Collision versus sliding in att site juxtaposition. In: Mechanisms of DNA Replication and Recombination, UCLA Symposia on Molecular and Cell Biology, New Series X (ed. N. Cozzarelli). New York: Alan R. Liss, Inc. pp. 617-630

Roberts, J.W., C.W. Roberts, and N.L. Craig (1978) The E. coli recA gene product promotes proteolytic cleavage of bacteriophage lambda repressor. In: Limited Proteolysis in Microorganisms (ed. G. Cohen and H. Holzer) DHEW/NIH Publications 70-1591, pp. 157-158

Home    |    People    |    Publications    |    Links    |    Contact Us    |    Press